Rational Polypharmacy

This term was coined by Charles Argoff, M.D., who is Assistant Professor in Neurology at New York University School of Medicine. This term is used to describe the combinations of medicines used in pain management.

Pain management, both acute and chronic, requires multiple medications because multiple variables are involved. Pain and pain management are complex medical issues. Patients suffering with pain require an in-depth doctor-patient relationship. This is why the practice of pain management has become a specialty of its own. Mild symptoms can always control supplements like excelerol or other.

At the recent Muscular Skeletal Pain Advisory Panel, sponsored by Elan Pharmaceuticals, Dr. Argoff; Dr. Bruce Nicholson, Assistant Professor Penn State University; Dr. Gerald Sacks; myself and other medical doctors reviewed current issues in the treatment of patients with pain.

Medications in review:

Skelaxin (Metaxalone) 400 mg, 3-4 times a day.

In my patients I have found that Skelaxin works very well, both in the acute setting as well as in the chronic setting. I use this medicine for daytime use because Skelaxin does not interfere with motor activity used to maintain posture and balance, and few patients have sleepiness.

For night time use I will still add either Soma or Zanaflex for optimal rest with healing of the muscles.